Protein Info for PfGW456L13_1822 in Pseudomonas fluorescens GW456-L13

Annotation: INTEGRAL MEMBRANE PROTEIN (Rhomboid family)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 transmembrane" amino acids 41 to 66 (26 residues), see Phobius details amino acids 70 to 92 (23 residues), see Phobius details amino acids 125 to 143 (19 residues), see Phobius details PF06271: RDD" amino acids 35 to 158 (124 residues), 68.1 bits, see alignment E=5.1e-23

Best Hits

KEGG orthology group: None (inferred from 81% identity to pfo:Pfl01_4439)

Predicted SEED Role

"INTEGRAL MEMBRANE PROTEIN (Rhomboid family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QMV3 at UniProt or InterPro

Protein Sequence (241 amino acids)

>PfGW456L13_1822 INTEGRAL MEMBRANE PROTEIN (Rhomboid family) (Pseudomonas fluorescens GW456-L13)
MLETTAQPRNAPLSPPLDTRYQVETPEGVDLPLRPAGLMVRALAFSIDLGLRGLVLGVLF
IVLAMLGKLGAGLGSILLFVVSWWYMVLFEVLNHGRSPGKQWMGLQVVHDDGTPVGWSAS
LLRNLLRVVDLLPFGYFLGAISCLQHPHFKRLGDIAAGTLVIYRERPHTRPQLPEARPRR
PAFVLTLTEQRAILGFAERQGELSEARVNELASILAHPLQVAPPQAVTELNGIARGLLGP
T