Protein Info for PfGW456L13_1786 in Pseudomonas fluorescens GW456-L13

Annotation: drug resistance transporter, EmrB/QacA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details amino acids 51 to 70 (20 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 141 to 162 (22 residues), see Phobius details amino acids 168 to 190 (23 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 233 to 251 (19 residues), see Phobius details amino acids 272 to 294 (23 residues), see Phobius details amino acids 307 to 326 (20 residues), see Phobius details amino acids 338 to 355 (18 residues), see Phobius details amino acids 361 to 384 (24 residues), see Phobius details amino acids 404 to 425 (22 residues), see Phobius details amino acids 474 to 497 (24 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 17 to 421 (405 residues), 254.7 bits, see alignment E=8.8e-80 PF07690: MFS_1" amino acids 21 to 413 (393 residues), 189.8 bits, see alignment E=1e-59 PF00083: Sugar_tr" amino acids 48 to 179 (132 residues), 50.9 bits, see alignment E=1.9e-17 PF06609: TRI12" amino acids 59 to 297 (239 residues), 43.2 bits, see alignment E=2.9e-15

Best Hits

KEGG orthology group: None (inferred from 90% identity to pfo:Pfl01_4479)

Predicted SEED Role

"drug resistance transporter, EmrB/QacA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QML7 at UniProt or InterPro

Protein Sequence (505 amino acids)

>PfGW456L13_1786 drug resistance transporter, EmrB/QacA family (Pseudomonas fluorescens GW456-L13)
VTNLHQPETPKPAIRSVLIALMLAIFLGALDQTIVAVSMPAISAQFKDVSLLAWVISGYM
VAMTVAVPIYGKLGDLYGRRKLMLFGMGLFTLASVFCGMAQSMEQLVLARIFQGIGAGGM
ISVSQAIIGDIVPPRERGRYQGYFSSMYAVASVAGPVLGGYMTEYLSWRWVFLINLPLGL
GAWLVAYRTLVGLPIPQRKPIIDYLGTVLMIIGLTALLLGITQVGQGHSWRSAEVLALLA
CAVLVLGLFVVHERRAREPLLPIHLFANRNAILCWCTIFFTSFQAISLIVLMPLRFQSVT
GAGADSAALHLLPLAMGLPIGAYFAGRRTSVTGRYKPMILTGAALMPVSIIGMAFSPPQA
FVVSSLFMLLCGISSGMQFPTSLVGTQNSVDQRDIGVATSTTNLFRSLGGAVGVALMSAL
LLALLQDSSFAHLAGSSLIAEGSSGNVLLDGLNAAPGDAQNTLRAELSLTFRHLLTVSAA
VSLLGLAAAIAMPNMLLRGREDKVR