Protein Info for PfGW456L13_1771 in Pseudomonas fluorescens GW456-L13
Annotation: RND multidrug efflux transporter; Acriflavin resistance protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 45% identical to Y895_HAEIN: Uncharacterized transporter HI_0895 (HI_0895) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG orthology group: None (inferred from 94% identity to pfo:Pfl01_4493)Predicted SEED Role
"RND multidrug efflux transporter; Acriflavin resistance protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A293PYJ0 at UniProt or InterPro
Protein Sequence (1008 amino acids)
>PfGW456L13_1771 RND multidrug efflux transporter; Acriflavin resistance protein (Pseudomonas fluorescens GW456-L13) MAFTDPFIRRPVLATVVSLLIVLLGFQAWSKLPLRQYPQMENALITVTTAYPGANAETIQ GYITQPMQQSLASAEGIDYMTSVSRQNFSVISIYARVGANSDRLFTELLAKANEVKNQLP QDAEDPVLSKESADASVLMYISYFSKELSNPQITDYLSRVIQPKLATLPGMAEAEILGNQ VFAMRLWLDPMKLAGFGLSASDVTNAVRQYNFLSAAGEVKGEYVVTSINANTELKSAEAF GTIPLKVDGDSRVLLRDVARVEMGAENYDSISSFGGTPSVYIGIKATPGANPLEVIKEVR KIMPDLEAQLPPNLNGEIAYDATLFIQASIDEVVKTLFEAVLIVIVVVFLFLGALRSVVI PVVTIPLSMIGVMFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKTPL EAAIEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVVISGIVALTL SPMMCAFLLRHDENPSGLAHRLDMIFERLKRRYQSLLHGTLNTRPVVLVFAVIVLCLIPV LLNFTKSELAPDEDQGIIFMIANAPQPTNLDYLNTYTDEFVSIFKAFPEYYSSFQINGFN GVQSGIGGFLLKPWDDRSRTQMAILPEVQAKLEKIPGLQIFGFNLPSLPGTGEGVPFQFV INSANDYELLLQVVDRVKKRAKESGKFAFVHVDLAFDKPEVVVDIDRAKAAQMGVSMQDL GGTLATLLGEGEINRFTIEGRSYKVIAQVERPFRDNPDWLNNYYVKNTKGELLALSTLIT VTDRARPRQLNQFQQLNSAILSGVPLVSMGEAIDLVRQIAREEAPAGFAFDYAGASRQYV QEGSALWVTFALALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGWSSMNIYT QVGLVTLIGLISKHGILIVEFANQLRKDKGLSAREAVEEAAAIRLRPVLMTTAAMVFGMV PLIIASGAGAVSRFDIGTVIATGMSIGTLFTLFVLPCVYTLLAKPDKR