Protein Info for PfGW456L13_159 in Pseudomonas fluorescens GW456-L13

Annotation: NAD(P)HX epimerase / NAD(P)HX dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 TIGR00197: YjeF family N-terminal domain" amino acids 12 to 210 (199 residues), 137.2 bits, see alignment E=6e-44 PF03853: YjeF_N" amino acids 34 to 192 (159 residues), 133.8 bits, see alignment E=6.1e-43 TIGR00196: YjeF family C-terminal domain" amino acids 234 to 491 (258 residues), 225.6 bits, see alignment E=7.7e-71 PF01256: Carb_kinase" amino acids 250 to 471 (222 residues), 207.7 bits, see alignment E=2e-65

Best Hits

KEGG orthology group: None (inferred from 82% identity to pfo:Pfl01_0518)

Predicted SEED Role

"NAD(P)HX epimerase / NAD(P)HX dehydratase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QIT8 at UniProt or InterPro

Protein Sequence (499 amino acids)

>PfGW456L13_159 NAD(P)HX epimerase / NAD(P)HX dehydratase (Pseudomonas fluorescens GW456-L13)
MPHTKDELPDVLYSTAQVRALDASLIAAGTAGFELMQRAARATWRALVRQWPTANELSVL
AGHGNNAGDGYLVAVLAQRAGWSVRVLAVGDPQRLQGDAASAHAEAVSEQVLIEPWTAQS
GLRGIVVDALLGTGLSGDVRDPYVSAIAAINASGLPVAAVDIPSGLCADTGRILGHAVHA
DLTVTFIGLKVGLFTGDAADVTGELVFNDLQADPQLLNGTAFTARRLCIANLPRLVSRAP
ASHKGKFGHVLLIGGDRGYGGAILLSAQSALRSGAGMVSLSTRPEHVSPALSRIPEAMVL
GTSSANQLMELLEKVSVLVVGPGLGQAGWGRSLLSAAANAPLPQVWDADALNLLAGGQVD
LPKGCVITPHPGEAARLLGVSTADVQFDRPAAAHALSKKYTAVVVLKGAGSLIAHPDGRL
ALCHQGHPAMATAGLGDVLAGLLGALLAQGMEPFDAACLAVWLHANAGEQQGKLGRGLAA
SDLIPAIRQLLEEQAPCLK