Protein Info for PfGW456L13_1586 in Pseudomonas fluorescens GW456-L13

Annotation: Lipid A 3-O-deacylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 147 PF09411: PagL" amino acids 14 to 145 (132 residues), 149.6 bits, see alignment E=3.2e-48

Best Hits

Swiss-Prot: 65% identical to PAGL_PSEAE: Lipid A deacylase PagL (pagL) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 84% identity to pba:PSEBR_a4754)

Predicted SEED Role

"Lipid A 3-O-deacylase" in subsystem Lipid A modifications

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJW8 at UniProt or InterPro

Protein Sequence (147 amino acids)

>PfGW456L13_1586 Lipid A 3-O-deacylase (Pseudomonas fluorescens GW456-L13)
VEFAVGQTGESTMTYRLGMQFDWDQSWWQSDVGRLTGYWDGAYTYWEGDEKSSNHSLSFS
PVLVYEFAGQNVKPYIEFGIGVAAFASTEVESNDLGSAFQFEDRFGFGLRFAGGHEVGVR
ATHYSNAGITTPNDGVESYALHYTMPL