Protein Info for PfGW456L13_1557 in Pseudomonas fluorescens GW456-L13

Annotation: L-Proline/Glycine betaine transporter ProP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 32 to 60 (29 residues), see Phobius details amino acids 71 to 92 (22 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 131 to 157 (27 residues), see Phobius details amino acids 170 to 193 (24 residues), see Phobius details amino acids 205 to 223 (19 residues), see Phobius details amino acids 258 to 281 (24 residues), see Phobius details amino acids 296 to 317 (22 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 353 to 376 (24 residues), see Phobius details amino acids 387 to 405 (19 residues), see Phobius details amino acids 411 to 433 (23 residues), see Phobius details PF00083: Sugar_tr" amino acids 34 to 245 (212 residues), 78.4 bits, see alignment E=5.5e-26 PF07690: MFS_1" amino acids 50 to 399 (350 residues), 115.3 bits, see alignment E=3e-37

Best Hits

KEGG orthology group: None (inferred from 93% identity to pfo:Pfl01_4767)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QHI2 at UniProt or InterPro

Protein Sequence (449 amino acids)

>PfGW456L13_1557 L-Proline/Glycine betaine transporter ProP (Pseudomonas fluorescens GW456-L13)
MGALVFACARVLFMTNTDSLPKPFSRSDYKTLGLAALGGALEIYDFIIFVFFALTLSQLF
FPPEMPEWLRLLQSFGIFVTGYLARPLGGILMAHFADRLGRKKVFSLSILMMALPCLLIG
IMPTYAQIGYFAPLLLLALRILQGAAVGGEVPSAWVFVAEHAPIAHRGYALGFLQAGLTF
GYLIGALTATFLAQAFTAAEILDYAWRYPFLLGGVFGVIGVWLRRWLSETPVFTAMQAQR
EAAGELPLRTVLREHRLAILPAMILTCVLTSAVVVFVVITPTMMQKTFGMTASRTFALSA
LGIVFLNIGCVLAGLLVDRIGAWRTVMLYSLLLPLGIGVLYACLIMGGDWSGLAYAVAGL
SCGVVGAVPSVMVSLFPARIRVSGISFTYNIAYAAWASVTPLLLIGLMPWSPWICVMFSA
VMGAVGMGSAAYFGARMPRISGCPAAGAH