Protein Info for PfGW456L13_1496 in Pseudomonas fluorescens GW456-L13

Annotation: NADH dehydrogenase (EC 1.6.99.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07992: Pyr_redox_2
  • amino acids 4 to 337 (334 residues), 183 bits, E=1.8e-57
• PF00070: Pyr_redox
  • amino acids 170 to 254 (85 residues), 41.7 bits, E=2.8e-14

Best Hits

KEGG orthology group: K03885, NADH dehydrogenase [EC: 1.6.99.3] (inferred from 96% identity to pfo:Pfl01_4831)

Predicted SEED Role

"NADH dehydrogenase (EC 1.6.99.3)" in subsystem Carboxysome or Respiratory dehydrogenases 1 (EC 1.6.99.3)

MetaCyc Pathways

• aerobic respiration III (alternative oxidase pathway) (3/3 steps found)
• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• Fe(II) oxidation (3/6 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.99.3

Use Curated BLAST to search for 1.6.99.3

Sequence Analysis Tools

See A0A293PY31 at UniProt or InterPro

Protein Sequence (432 amino acids)

>PfGW456L13_1496 NADH dehydrogenase (EC 1.6.99.3) (Pseudomonas fluorescens GW456-L13)
MSHRIVIVGGGAGGLELATRLGKTLGKRGTASVMLVDANLTHIWKPLLHEVAAGSLNSSE
DELNYVAQAKWNHFEFQLGRMSGLDRAKKKIQLAATYDEAGLELVPAREVPYDSLVISVG
STTNDFGTQGAAQHCLFLDTRKQAERFHQQLLNHYLRAHAAQTDTIEQISVAIVGAGATG
VELAAELHNAAHELAAYGLDRIKPENMHITLIEAGPRVLPALPERIGGPVHKTLEKLGVN
VMTNAAVSEVTADSLITADGNEIKASLKVWAAGIRAPGFLKDIDGLETNRINQLQVLPTL
QTTRDENIFAFGDCAACPQPGSDRNVPPRAQAAHQQASLLAKSLKLRIEGKALPEYKYTD
YGSLISLSRFSAVGNLMGNLTGSVMLEGWLARMFYVSLYRMHQMALYGPFRTAMLMLGSK
IGRGTEPRLKLH