Protein Info for PfGW456L13_1494 in Pseudomonas fluorescens GW456-L13

Annotation: COG1496: Uncharacterized conserved protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 239 PF02578: Cu-oxidase_4" amino acids 20 to 238 (219 residues), 248.2 bits, see alignment E=3.9e-78 TIGR00726: YfiH family protein" amino acids 25 to 239 (215 residues), 196.7 bits, see alignment E=1.7e-62

Best Hits

Swiss-Prot: 73% identical to POLOX_PSEAE: Polyphenol oxidase (PA4543) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K05810, conserved hypothetical protein (inferred from 86% identity to pfo:Pfl01_4835)

Predicted SEED Role

"COG1496: Uncharacterized conserved protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QHC5 at UniProt or InterPro

Protein Sequence (239 amino acids)

>PfGW456L13_1494 COG1496: Uncharacterized conserved protein (Pseudomonas fluorescens GW456-L13)
MSDWLIPDWPAPAGVKACVTTRAGGVSVAPFDSLNLGDHVDDSPEAVAENRRRLTDHFSI
QPAWLQQVHGIVVAHANPGRVDTADASWTSTPGVACAAMTADCLPALFCDRAGTRVAAAH
AGWRGLAAGVLEATLDSLAVPPAEVLVWLGPAIGPQAFEVGSEVRETFVQQLPQAAEAFV
PSQNPGKFMADIYMLARLRLAARGVTAVYGGGFCTVTDPRFFSYRRAPRTGRFASLIWL