Protein Info for PfGW456L13_1438 in Pseudomonas fluorescens GW456-L13

Annotation: 23S rRNA (guanine-N-2-) -methyltransferase rlmG (EC 2.1.1.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05175: MTS
  • amino acids 201 to 371 (171 residues), 175.4 bits, E=2.5e-55
• PF06325: PrmA
  • amino acids 231 to 306 (76 residues), 34.9 bits, E=3.6e-12
• PF13847: Methyltransf_31
  • amino acids 233 to 312 (80 residues), 38.4 bits, E=3.2e-13
• PF13649: Methyltransf_25
  • amino acids 235 to 335 (101 residues), 30.7 bits, E=1.2e-10
• PF08242: Methyltransf_12
  • amino acids 237 to 335 (99 residues), 31.8 bits, E=6e-11

Best Hits

Swiss-Prot: 91% identical to RLMG_PSEPF: Ribosomal RNA large subunit methyltransferase G (rlmG) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K00564, ribosomal RNA small subunit methyltransferase C [EC: 2.1.1.172] (inferred from 91% identity to pfo:Pfl01_4890)

Predicted SEED Role

"23S rRNA (guanine-N-2-) -methyltransferase rlmG (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

• Alkaloid biosynthesis I
• Anthocyanin biosynthesis
• Benzoxazinone biosynthesis
• Biosynthesis of alkaloids derived from shikimate pathway
• Carotenoid biosynthesis - General
• Flavonoid biosynthesis
• Histidine metabolism
• Insect hormone biosynthesis
• Naphthalene and anthracene degradation
• Phenylpropanoid biosynthesis
• Porphyrin and chlorophyll metabolism
• Tryptophan metabolism
• Tyrosine metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-, 2.1.1.172

Use Curated BLAST to search for 2.1.1.- or 2.1.1.172

Sequence Analysis Tools

See A0A293QLM7 at UniProt or InterPro

Protein Sequence (374 amino acids)

>PfGW456L13_1438 23S rRNA (guanine-N-2-) -methyltransferase rlmG (EC 2.1.1.-) (Pseudomonas fluorescens GW456-L13)
MPLLETPFASLDLIRQPEQQNEPLQAFDAADEYLLNHLAEQQPASDTRVLVLNDSFGALA
ASLVGKVRVVSSGDSFLAFQGLEKNLVRNGLAFDAVPSVPASETPAGPFDCVLIRVPKTL
ALLEEQLIRLQGQLAPGAQVVAAAMIKHLPRAAGDLLERYIGPVQASLAVKKARLLIATA
EDKTPAVSPYPTRYRLDEPAIELLNHANVFCREGLDIGTRAFLPHLPKNLGSARVADLGC
GNGVLAIASALQNPEAHYTLVDESYMAVQSASENWRAALGEREVIVRAGDGLAGQEPQSL
DVVLCNPPFHQQQVVGDFLAWRMFQQAREALVVGGALYIVGNRHLGYHSKLARLFRGVEQ
VAANPKFVILKARK