Protein Info for PfGW456L13_1433 in Pseudomonas fluorescens GW456-L13

Annotation: DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 PF01965: DJ-1_PfpI" amino acids 4 to 167 (164 residues), 130.2 bits, see alignment E=3.5e-42 TIGR01383: DJ-1 family protein" amino acids 5 to 177 (173 residues), 155.1 bits, see alignment E=8.3e-50

Best Hits

KEGG orthology group: K03152, 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis (inferred from 86% identity to pfl:PFL_5370)

Predicted SEED Role

"DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QLS5 at UniProt or InterPro

Protein Sequence (183 amino acids)

>PfGW456L13_1433 DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31 (Pseudomonas fluorescens GW456-L13)
MTFRALIALAEGTDDLQTVTLIDVLRRAKIEVVVASIEGRRMLTCARGTRLTSDAMLVDL
LAQPFDLIALPGGAVGSQHLAAHQPLQQLVKDQAAAGRLFAGIAEAPAVALQAFGVLRQR
RMTCLPSASHQLLGCTFVDQPVVVDGNCITAQGSAGALAFSLALVEQLCGKATRMAVAGE
LLV