Protein Info for PfGW456L13_1398 in Pseudomonas fluorescens GW456-L13

Annotation: Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 34 to 442 (409 residues), 270.3 bits, E=1.2e-84

Best Hits

Swiss-Prot: 51% identical to SPUC_PSEAE: Putrescine--pyruvate aminotransferase (spuC) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 97% identity to pfo:Pfl01_4932)

MetaCyc: 51% identical to putrescine--pyruvate aminotransferase (Pseudomonas aeruginosa)
RXN-8 [EC: 2.6.1.113]

Predicted SEED Role

"Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.18)

MetaCyc Pathways

• superpathway of coenzyme A biosynthesis II (plants) (9/10 steps found)
• β-alanine biosynthesis II (5/6 steps found)
• β-alanine degradation II (2/2 steps found)
• putrescine degradation V (2/2 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.18

Use Curated BLAST to search for 2.6.1.113 or 2.6.1.18

Sequence Analysis Tools

See A0A293QH21 at UniProt or InterPro

Protein Sequence (456 amino acids)

>PfGW456L13_1398 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) (Pseudomonas fluorescens GW456-L13)
MTTPRDTRDYQAADAAHHIHAFVDQKALNDEGPRVMVRGERLHLWDNDGRRYLDGMSGLW
CTNLGYGRKDLAAAASRQLEQLPYYNMFFHTTHPQVIELSELLFSLLPAHYSHAIYTNSG
SEANEVLIRTVRRYWQVLGKPEKKIMIGRWNGYHGSTLAATALGGMKFMHEMGGMIPDIE
HIDEPYFFAHEGNLTPAEFGLRAAQQLEAKILELGADKVAGFIAEPFQGAGGMIFPPESY
WPEIQRICRKYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYIPMGGLI
LSKKMASVLVEQGGVFAHGLTYSGHPVAAAVAIANLKALRDEGVVTRVKDDIGPYLQQCL
REVFGKHPLVGDIQGTGMVAALQLAEDKTSRKRFANENDIAWRCRTIGFEEGVIIRSTLG
RMIMAPALIASREEIDELIAKTLKAVDRTAQEYGRL