Protein Info for PfGW456L13_1324 in Pseudomonas fluorescens GW456-L13

Annotation: Outer membrane vitamin B12 receptor BtuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07715: Plug" amino acids 46 to 151 (106 residues), 102 bits, see alignment E=2.6e-33 PF00593: TonB_dep_Rec" amino acids 186 to 591 (406 residues), 153.3 bits, see alignment E=2e-48

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 86% identity to pfo:Pfl01_5008)

Predicted SEED Role

"Outer membrane vitamin B12 receptor BtuB" in subsystem Coenzyme B12 biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QGV3 at UniProt or InterPro

Protein Sequence (627 amino acids)

>PfGW456L13_1324 Outer membrane vitamin B12 receptor BtuB (Pseudomonas fluorescens GW456-L13)
MKLSPFALTLTLLPAGQLLADTFERDQALKLPDVLISANRQVEARNDSSAANTVFTRDDI
DRLQPDSVTDLLRRVPGVQVSQSGGRGSIPGVYIRGTQSAQSLVLVDGQRIGSSTSGDSN
LQHINIEQVERVEVLRGSRSVIYGSDAIGGVIQIFTRRGGEQGLQPRMHTGFGSNQTWER
SLGLSGGDERTRFNLGASLDETAGINRTHESYPSDGDHDAYRNKSLSLSLSHTLTEDVEV
GANVLDNRGKSEFDSPFGRYDYVTDKSYQQQPYNDFNVSSVSSYIDAQINEVWKTRVELG
HSENRETTLDKLSDERSVFNTYRDSVNWQNDLTLNERNSLMLGGDWYEDRINSTTAFDED
SRWNRAVFIQHRFQTDSFSTELGLRHDDNQQFGSQNTWSGTFTVPLNPDNEVLLTYSEGF
RAPTFNDLYYPDFSNPDLKPETSKSYELQWRSQLTESSRLETSLYRTDLEDAIIFGSNSR
PENVASARINGFEAALKQELFGWQSNLGVAIIDPRDRDTGHTLARRARRTLSLDLDRQFD
RLGLGASWQAVSSSYDDLNNQQPLGGYALLGLRSSWELNREIKLELKVDNLLDKGYSRAL
YSYQGSQYGYREEGRAWMFGVTWTPEI