Protein Info for PfGW456L13_1202 in Pseudomonas fluorescens GW456-L13

Annotation: Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13624: SurA_N_3" amino acids 23 to 146 (124 residues), 48.6 bits, see alignment E=2.5e-16 PF13623: SurA_N_2" amino acids 26 to 110 (85 residues), 32.4 bits, see alignment E=2.4e-11 PF09312: SurA_N" amino acids 30 to 147 (118 residues), 147.2 bits, see alignment E=7.1e-47 PF13616: Rotamase_3" amino acids 172 to 279 (108 residues), 62.3 bits, see alignment E=1.9e-20 amino acids 278 to 386 (109 residues), 106.5 bits, see alignment E=3.7e-34 PF00639: Rotamase" amino acids 184 to 275 (92 residues), 69.9 bits, see alignment E=9.4e-23 amino acids 293 to 383 (91 residues), 90.8 bits, see alignment E=2.8e-29 PF13145: Rotamase_2" amino acids 198 to 288 (91 residues), 41.1 bits, see alignment E=9e-14 amino acids 293 to 388 (96 residues), 31.7 bits, see alignment E=7.1e-11

Best Hits

Swiss-Prot: 89% identical to SURA_PSEPF: Chaperone SurA (surA) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 89% identity to pfl:PFL_5647)

MetaCyc: 42% identical to chaperone SurA (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QVA6 at UniProt or InterPro

Protein Sequence (438 amino acids)

>PfGW456L13_1202 Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) (Pseudomonas fluorescens GW456-L13)
VKTKLSDCLRPLMLGALFLSTAANAAVQSIDKVVAIVDNDVVMQSQLDQRVHEVQQTIAK
RGSAVPPASVLEQQVLERLIVENLQLQIGERSGIRITDEELNQAVGTIAQRNNMSVEQFR
AALTRDGLSYDDAREQIRREMVISRVRQRRVAERIQVSEQEVKNFLASDLGKMQLSEEFH
LANILIPTPESANSDAIQSAAKQADAIYQQLKQGADFSQLAIAKSASETALEGGDMGWRK
AAQLPPPFDRLLSTMPVGDVTQPMRTPGGFIILKILEKRGGQTQMRDEVHVRHILVKPSP
IRDEAKTKALADSLYSRIEAGEDFGELAKSYSEDPGSALNGGDLNWIDPNALVPEFREVM
ASTPQGQLSKPFQTQYGWHVLEVLGRRATDSTTQAREQQAMTVLRNRKYDEELQTWLRQI
RDEAYVEIKLPGADQAAQ