Protein Info for PfGW456L13_1185 in Pseudomonas fluorescens GW456-L13

Annotation: sensory box/GGDEF domain/EAL domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1248 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 268 to 289 (22 residues), see Phobius details PF00497: SBP_bac_3" amino acids 39 to 256 (218 residues), 139.3 bits, see alignment E=5.7e-44 TIGR00229: PAS domain S-box protein" amino acids 308 to 433 (126 residues), 43.7 bits, see alignment E=2.9e-15 amino acids 436 to 557 (122 residues), 49.5 bits, see alignment E=4.4e-17 amino acids 559 to 682 (124 residues), 48.8 bits, see alignment E=7.5e-17 amino acids 687 to 804 (118 residues), 64.8 bits, see alignment E=8.4e-22 PF08447: PAS_3" amino acids 337 to 412 (76 residues), 37.7 bits, see alignment 8.4e-13 amino acids 707 to 790 (84 residues), 27.3 bits, see alignment 1.5e-09 PF13426: PAS_9" amino acids 449 to 549 (101 residues), 28.8 bits, see alignment E=4.9e-10 amino acids 572 to 674 (103 residues), 30.6 bits, see alignment E=1.3e-10 amino acids 694 to 795 (102 residues), 50 bits, see alignment E=1.2e-16 PF13188: PAS_8" amino acids 686 to 726 (41 residues), 28.1 bits, see alignment (E = 5.9e-10) PF00989: PAS" amino acids 687 to 794 (108 residues), 42.4 bits, see alignment E=2.5e-14 PF08448: PAS_4" amino acids 689 to 797 (109 residues), 27.8 bits, see alignment E=1e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 804 to 967 (164 residues), 141.4 bits, see alignment E=2.3e-45 PF00990: GGDEF" amino acids 808 to 965 (158 residues), 169.1 bits, see alignment E=2.7e-53 PF00563: EAL" amino acids 986 to 1220 (235 residues), 254.7 bits, see alignment E=3.1e-79

Best Hits

KEGG orthology group: None (inferred from 93% identity to pfo:Pfl01_5150)

Predicted SEED Role

"sensory box/GGDEF domain/EAL domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QKZ6 at UniProt or InterPro

Protein Sequence (1248 amino acids)

>PfGW456L13_1185 sensory box/GGDEF domain/EAL domain protein (Pseudomonas fluorescens GW456-L13)
MPRLPTVLFLLSLMTWTATAGALTLTDEERSWLAAHPELRLGVDASWPPFEFRDDEGRYQ
GLAADYIEVIRKRLATRLTPIEPVSWTAVLEQAKKGKLDLLPGIMSTPERQNYLSFTRPY
LDFPIVILAHVGGPQPHNLKDLYGLKIAVVENYAPHELLRTHHPDLNLVAMPNVSSALQA
LAIDEVDAVVGDLASSVWSLRQLKLDGLYVSGETPYRYQLAMGVPRNNKMLVGILDKVLA
DMSPAEISAIQEHWVGNVLDHRTFWSDLLVYGLPGLLLLTTVLAVVIRINRRLSSEIARR
VDLEQELRSSEYHYRGLVESLSAIAWEAKVTDFTYSYVSPHAEDLLGYPLSHWLIPGFWR
NIIHPADLTRAQTFCDHEVLAGRDHRLDYRVITADGRCLWVRDIVSLIEHGHEPVLRGLM
IDITDAKRTEEALRLSEQKFASVFQQCPDILVIARLSDGCLLEVNDAFEEQIGLKAEDVI
GQTATNLNIWGIPGVGPGLLQRLQAGSIRNLEMPFRRSNGHVFTGLISAEPFDLDMTPAL
VVVVRDITQLKETQQQLQTSEEKFAKAFHASPDGLLLSRQSDGLLLEVNDGFSRITGFNS
AMSVDRSALDLGIWVNLNERKQMLDLLRRDGFVRDFSCHIRRSDGQIRLCEVSSRPLPIG
DDDCMLTIARDITERHLMQEKLQQAATVFESTAEGVLITDTQQHISAVNRAFTEITGYSE
NEALGHTPRLLASGLHDSAFYAAMWHQLTAEGHWQGEISNRRKNGELYPSWLTISAVRNR
ENFITHFVAVFADISSLKHAQAKLDYQAHHDPLTGLPNRTLFESRLLTALNSQQENGGQG
AVLFLDLDRFKHINDSLGHPVGDLLLKGIAVRLKEQLRDIDTVARLGGDEFIILLPGLQQ
SSDADHIATKLLNCFAAPFQAGEHEFFISASIGTSLYPKDGCDVATLIKNADAAMYRSKA
KGRNRVESYTRDLTAQASERVALEHELRRAIERNELRLCYQPKISLEDYSLVGAEALIRW
HHPTFGDVPREHFIPLAEENGMILQIGDWVLETACRQMAEWHRLYENPGPLSVNLAGAQL
RQPNLLGRIEQLLKDNGLNPGFLQLEITENFIMSQAEEALAVLHQLKQLGVQLAIDDFGT
GYSSLSYLKRLPLDILKIDQSFVRGLPDDPHDAAIVRAIIALGRSMQFTVIAEGVETHAQ
QQFLAAEGCEQIQGYIVSLPLPPDEFAATFLRTAVKAFSDSTVAKPSL