Protein Info for PfGW456L13_1137 in Pseudomonas fluorescens GW456-L13

Annotation: Predicted signal-transduction protein containing cAMP-binding and CBS domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 PF00027: cNMP_binding" amino acids 36 to 122 (87 residues), 35.1 bits, see alignment E=2.2e-12 PF00571: CBS" amino acids 166 to 218 (53 residues), 39.7 bits, see alignment 1e-13 amino acids 231 to 281 (51 residues), 37.4 bits, see alignment 5.3e-13 PF03445: DUF294" amino acids 309 to 448 (140 residues), 143.2 bits, see alignment E=1e-45 PF10335: DUF294_C" amino acids 485 to 628 (144 residues), 149.4 bits, see alignment E=1.2e-47

Best Hits

KEGG orthology group: K07182, CBS domain-containing protein (inferred from 92% identity to pfo:Pfl01_5185)

Predicted SEED Role

"Predicted signal-transduction protein containing cAMP-binding and CBS domains" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJ89 at UniProt or InterPro

Protein Sequence (630 amino acids)

>PfGW456L13_1137 Predicted signal-transduction protein containing cAMP-binding and CBS domains (Pseudomonas fluorescens GW456-L13)
VLQNIQGTLQFLQRFPPFNQMEHAHLAYLVEQCQMRFYAPGESIIKPADGPVEHFYIVKQ
GRVVGERPHTVNGSTETVFEITTGECFPLAALLGERATRTEHLAGEDTFCLQLNKPAFIR
LFSLSDTFRNFALRCVSSLLDQVNQQVQQKAVETLGTQYSLNTRLGELAMRHPVTCAPQT
PLREAVTLMHEQQVGSIVVVDELKAPLGIFTLRDLRQTVANGSSDFNEAIEGYMTRAPFF
LSPDQSAFDAAIAMTERHIAHVCLVKDQRLCGVVSERDLFSLQRVDLVHLARTIRNAQKV
ENLMALRGEIGQLVERMLAHGASSTQITHIITLLNDHTVCRVIELTLAEKGDPGVPFSWL
CFGSEGRREQTLHTDQDNGILFEARDAAHAAEIRGKLLPIAQQINQSLALCGFTLCKGNI
MAGNPELCLSRAEWARRFAAFIREATPENLLGSSIYFDLRVVWGSEQGCEQLRRSILDQV
GDNRLFQRMMAENALRNRPPVGRFREFVLARKNGEKATLDLKTQGLTPFVDGARLLALAH
GIETNNTLERFRQLVDKEVIDPLDGAAYEEAYHFIQQTRMQQHQLQTRENFPYSNRVDPD
SLNHLDRRILRESLRQAQRLQSSLTLRYQI