Protein Info for PP_5748 in Pseudomonas putida KT2440

Annotation: cytochrome c heme lyase subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 158 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 104 to 125 (22 residues), see Phobius details PF03918: CcmH" amino acids 10 to 151 (142 residues), 189.8 bits, see alignment E=7.2e-61

Best Hits

Swiss-Prot: 71% identical to CCMH_PSEFL: Cytochrome c-type biogenesis protein CcmH (ccmH) from Pseudomonas fluorescens

KEGG orthology group: K02200, cytochrome c-type biogenesis protein CcmH (inferred from 99% identity to ppf:Pput_1547)

Predicted SEED Role

"Cytochrome c heme lyase subunit CcmL" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A140FWM4 at UniProt or InterPro

Protein Sequence (158 amino acids)

>PP_5748 cytochrome c heme lyase subunit (Pseudomonas putida KT2440)
MRRWLAAAVLGMSLAGVAKAAIDTYQFRDEAERERYQQLTKELRCPKCQNQDIADSNAPI
AADLRREIFRMLGEGQSNQQIIDFMVDRYGDFVRYKPALSGRTWLLWFGPGILLAGGFVV
LAVIVRRRRATAVQGADELSAEERERLAKLLEKEQTHD