Protein Info for PP_4929 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 PF00126: HTH_1" amino acids 12 to 71 (60 residues), 64.4 bits, see alignment E=7.2e-22 PF03466: LysR_substrate" amino acids 99 to 293 (195 residues), 110.2 bits, see alignment E=9.4e-36

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_4929)

Predicted SEED Role

"LysR family transcriptional regulator PA4989" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88D98 at UniProt or InterPro

Protein Sequence (301 amino acids)

>PP_4929 Transcriptional regulator, LysR family (Pseudomonas putida KT2440)
MGDRLMAEQWNLEQLRTFLRVAELRSFSAVAREQHKAQSAISSAIALLETDLGVTLFERS
SGRQPKLTENGSALLEDARELLRQCERLDGRALALMRGQEALLRVAQDEAMPYQPVIDSL
DELASRYPFLEVQLASGAQGDVARKLVERRADLGLFFLHESIPASLERRALGSVEMVTVC
AVGHPLAGEGRVTRQQLARHRQLLITPQQSGYPGGEAISPQVWRADSFYAMAELLMRGLG
WAWLPRHVVQYPTYQAHMVELDSDWRPPALVAELAWRRDEPLGPAAQWLAERFAVHLRAI
G