Protein Info for PP_4825 in Pseudomonas putida KT2440

Annotation: Membrane protein, MarC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 40 to 59 (20 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details amino acids 106 to 126 (21 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details PF01914: MarC" amino acids 3 to 195 (193 residues), 136.8 bits, see alignment E=3.4e-44 TIGR00427: membrane protein, MarC family" amino acids 5 to 192 (188 residues), 119.6 bits, see alignment E=7.5e-39

Best Hits

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 97% identity to ppg:PputGB1_4878)

Predicted SEED Role

"membrane protein, MarC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DK0 at UniProt or InterPro

Protein Sequence (198 amino acids)

>PP_4825 Membrane protein, MarC family (Pseudomonas putida KT2440)
MLHELFSVYLKMLVLYSPFFVLSCFISLTRGHSSKERKQLAWKVAFAALVASVLLYLFGR
AIFGIFGITADAFRIGAGSVLFISALGMAQGKPAVQADNVQQDVTIVPLTIPLTVGPGTI
GALLVMGVSQPHWDEKLLAIVSIALASFTVGLVLYLSHGIERLLGDQGLQIVSRLMGLFV
CALAAQIIFTGIRGYLLP