Protein Info for PP_4787 in Pseudomonas putida KT2440

Annotation: putative protein with nucleoside triphosphate hydrolase domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 PF02562: PhoH" amino acids 113 to 316 (204 residues), 327.7 bits, see alignment E=4e-102 PF13604: AAA_30" amino acids 119 to 269 (151 residues), 30.6 bits, see alignment E=4.2e-11 PF13245: AAA_19" amino acids 120 to 269 (150 residues), 29.9 bits, see alignment E=8.5e-11

Best Hits

KEGG orthology group: K06217, phosphate starvation-inducible protein PhoH and related proteins (inferred from 100% identity to ppu:PP_4787)

Predicted SEED Role

"Phosphate starvation-inducible protein PhoH, predicted ATPase" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DN7 at UniProt or InterPro

Protein Sequence (332 amino acids)

>PP_4787 putative protein with nucleoside triphosphate hydrolase domain (Pseudomonas putida KT2440)
MNAPIEPHRFILEPFEAHRFANLCGQFDEHLRLIEQRLAIEIRNRGNQFELIGEPRTTSA
AEQLLRRLYRETKATDLSPETVHLYLQESAVENIDNPAVNEVSVSLRTRKGNIRPRGLNQ
QRYVKEILANDINFGIGPAGTGKTYLAVACAVDALEREQVRRILLVRPAVEAGEKLGFLP
GDLAQKIDPYLRPLYDALYEMLGFEHVAKLIERQVIEIAPLAYMRGRTLNNSFIILDESQ
NTTLEQMKMFLTRIGFGSTAVITGDITQVDLPRGTKSGLAHVIEVLKDVPGISFTHFQPK
DVVRHPLVQRIVEAYDRFEARQPKPEASGKDA