Protein Info for PP_4759 in Pseudomonas putida KT2440

Annotation: transcriptional regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 PF00392: GntR" amino acids 17 to 76 (60 residues), 71.5 bits, see alignment E=3.8e-24 PF07729: FCD" amino acids 97 to 224 (128 residues), 89.5 bits, see alignment E=2.4e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_4759)

Predicted SEED Role

"Predicted D-glucarate or D-galactorate regulator, GntR family" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DR4 at UniProt or InterPro

Protein Sequence (233 amino acids)

>PP_4759 transcriptional regulator, GntR family (Pseudomonas putida KT2440)
MEPEHARKRGHSRAHDLVSSLTQQILLGTFKPGDKLPSENTLVREHGVSRTVVREALSKL
QASGLVEPRHGIGTFVMERQAQAGLRVAAESAANVRDLLELRIGLEGQAAALAALRRDEG
HLARMRQALDDYQDLAAAGDSCIEADRRFHLLIAEATGNLYFTEMLLQLGNGLIPRNRMA
QAERAGAKLARQAYLANLEHEAILNAIRRQDPDAARAAVCLHLSNSRDRLLPD