Protein Info for PP_4752 in Pseudomonas putida KT2440
Annotation: putative Xaa-Pro aminopeptidase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to ppu:PP_4752)Predicted SEED Role
"Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)" in subsystem Protein degradation
MetaCyc Pathways
- glutathione degradation (DUG pathway) (2/2 steps found)
- γ-glutamyl cycle (4/6 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q88DS1 at UniProt or InterPro
Protein Sequence (435 amino acids)
>PP_4752 putative Xaa-Pro aminopeptidase (Pseudomonas putida KT2440) MQTGSDSIELLTALTERDLRFRSDAKVTEHAIAPVDTALLEAYAAIDRKALRHYRLERIR EQLRAQDYAGILLADPINIRYATDTNNLGLWVMHSPSRYVFVATDGPVVLFEFTSSQHNS EHVETIDEIRPAIPWLYFLAGPRVQEKAERWAQEVADLMARHGGGNRRLAVDRCDPWGAQ RLTHQGIELFDAQPLMEQARLIKSAEEVASHRVSMGVCDLAIARMRTSLVPGVTENQLWS IMHGTNVAHGGEWAESRLLSSGPRTNPWFQDATDKVIKAGEMVCFDTDMVGPGGYLSDIS RSFICPGKAPTMAQRDLLDIASQQINHNVELLRPGLSFREFAERCWPVPQRFEHNRYMMM LHGVGLVDEYPSVAYAVDFAEWGYDGLFQENMVVSVESYIGEQGGGEGVKLEEQVLISAN GPIKLSRTPLVDGDR