Protein Info for PP_4688 in Pseudomonas putida KT2440

Annotation: Heme/hemin ABC transporter, permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 70 to 91 (22 residues), see Phobius details amino acids 100 to 122 (23 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 161 to 185 (25 residues), see Phobius details amino acids 205 to 224 (20 residues), see Phobius details amino acids 255 to 279 (25 residues), see Phobius details amino acids 294 to 316 (23 residues), see Phobius details amino acids 322 to 341 (20 residues), see Phobius details PF01032: FecCD" amino acids 17 to 342 (326 residues), 295.2 bits, see alignment E=2.6e-92

Best Hits

Swiss-Prot: 41% identical to BTUC_PHOPR: Vitamin B12 import system permease protein BtuC (btuC) from Photobacterium profundum (strain SS9)

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 100% identity to ppu:PP_4688)

Predicted SEED Role

"Hemin ABC transporter, permease protein" in subsystem Hemin transport system or Iron acquisition in Vibrio or Putative hemin transporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DY0 at UniProt or InterPro

Protein Sequence (345 amino acids)

>PP_4688 Heme/hemin ABC transporter, permease protein (Pseudomonas putida KT2440)
MKRRVSPRTLFISLSLLCLLAIWLSLALGPVSLPMFDTLRAGLRLLGLPVSEDGLQQAEM
ILGQIRLPRTLLGLAVGAVLALSGVAMQGLFRNPLADPGLVGVAAGAAVGAAVAIVGGAW
FGGMPDAFAPYLLSFCAFVGGLGVTALVYRLGRRDGQTNVATMLLAGVAMTALGGAAVGL
FSYLADDATLRTLTFWNLGSLNGASYERLWPLLLVATGVAVWLPRRAKALNALLLGESEA
RHLGVDVERLKRELVFCTALGVGAAVAAAGLIGFIGLVVPHLVRLLAGPDHRVVLPASLL
AGGVLMLFADLAARLLLAPAELPIGIVTAFIGAPFFLFLLMRGRG