Protein Info for PP_4577 in Pseudomonas putida KT2440

Annotation: UPF0271 protein PP_4577

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF03746: LamB_YcsF" amino acids 15 to 253 (239 residues), 317.3 bits, see alignment E=3.7e-99

Best Hits

Swiss-Prot: 100% identical to PXPA2_PSEPK: 5-oxoprolinase subunit A 2 (pxpA2) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K07160, UPF0271 protein (inferred from 100% identity to ppu:PP_4577)

Predicted SEED Role

"Lactam utilization protein LamB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88E89 at UniProt or InterPro

Protein Sequence (258 amino acids)

>PP_4577 UPF0271 protein PP_4577 (Pseudomonas putida KT2440)
MHNDKGDRVVERLLLNCDMGESFGSWRMGLDAEVMPYIDCANIACGYHAGDPGIMRRTVT
LALEHGVTIGAHPAYPDLVGFGRRSMACSPEEIRDLLHYQIGALDGICKVLGGRVAYVKP
HGALYNDMMADPLKLRTVLEAVAAYDSNLPLMLMATADNRAAQALGDEIGVPLWFEAFAD
RAYTASGHLLSRRLPGAVHHDPARVVEQAVRLARGETLLADDGSALQLAARTLCVHGDND
SSVAAVRQIRQALDGLEV