Protein Info for PP_4575 in Pseudomonas putida KT2440
Annotation: Urea amidolyase-related protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to ppu:PP_4575)Predicted SEED Role
"Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54)" (EC 3.5.1.54)
MetaCyc Pathways
- L-arginine degradation V (arginine deiminase pathway) (4/4 steps found)
- L-citrulline degradation (3/3 steps found)
- cyanate degradation (2/3 steps found)
- urea degradation I (2/3 steps found)
- cyanuric acid degradation II (3/5 steps found)
- uracil degradation III (3/5 steps found)
- superpathway of allantoin degradation in yeast (3/6 steps found)
- cyanuric acid degradation I (2/5 steps found)
- superpathway of atrazine degradation (3/8 steps found)
- allantoin degradation IV (anaerobic) (2/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.54
Use Curated BLAST to search for 3.5.1.54
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q88E91 at UniProt or InterPro
Protein Sequence (305 amino acids)
>PP_4575 Urea amidolyase-related protein (Pseudomonas putida KT2440) MKQLMIEASTPLCQLQDAGRFGVRHLGVTQGGALDWVAMHWANWLLGNPLGAPVVEVALG GFCVVAEQDCVLALAGADLDACVDDQPLAPWRSFALAKGQRLTLKQPKVGVRAYLAAPGG FLGEDVLGSCATVVREALGGIDGQGAALAKHQALAFTGSNAPLREVPQALCPQFAQKPVL DLVMGAQIGEFSGTSLFEAFNREWTLDSRADRMGIRLLGPQLVYQGAPMISEGIPLGAVQ VPPDGQPIVLLNDRQTIGGYPRLGALTPLALAQLAQCMPGTVVRFRAVVQDEAWREQQLY LGRWS