Protein Info for PP_4485 in Pseudomonas putida KT2440

Annotation: histidine / lysine / arginine / ornithine ABC transporter - permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 transmembrane" amino acids 13 to 39 (27 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 91 to 109 (19 residues), see Phobius details amino acids 151 to 174 (24 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 8 to 115 (108 residues), 67.4 bits, see alignment E=6.4e-23 PF00528: BPD_transp_1" amino acids 32 to 221 (190 residues), 80.1 bits, see alignment E=9e-27

Best Hits

Swiss-Prot: 53% identical to HISQ_SALTI: Histidine transport system permease protein HisQ (hisQ) from Salmonella typhi

KEGG orthology group: K10024, arginine/ornithine transport system permease protein (inferred from 100% identity to ppg:PputGB1_3990)

Predicted SEED Role

"Arginine/ornithine ABC transporter, permease protein AotQ" in subsystem Arginine and Ornithine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88EH8 at UniProt or InterPro

Protein Sequence (229 amino acids)

>PP_4485 histidine / lysine / arginine / ornithine ABC transporter - permease subunit (Pseudomonas putida KT2440)
MLKGYGAVILDGAWLTLQLALSSMALAIVLGLIGVALRLSPVRWLAWLGDLYSTVIRGIP
DLVLILLIFYGGQDIINRVAPLLGYEDYIDLNPLIAGIGTLGFIFGAYLSETFRGAFLGI
PKGQAEAGVAYGMSPRQVFFRIQVPQMIRLAIPGFTNNWLVLTKATALISVVGLQDMMFK
AKQAADATREPFTFFLAVAALYLVLTSVSLLALKYLERRYSVGVKVAEL