Protein Info for PP_4295 in Pseudomonas putida KT2440

Annotation: TetR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 PF00440: TetR_N" amino acids 12 to 58 (47 residues), 60.2 bits, see alignment 1.3e-20 PF08362: TetR_C_3" amino acids 59 to 201 (143 residues), 213.3 bits, see alignment E=1.4e-67

Best Hits

KEGG orthology group: K09017, TetR/AcrR family transcriptional regulator (inferred from 100% identity to ppg:PputGB1_3860)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88F05 at UniProt or InterPro

Protein Sequence (203 amino acids)

>PP_4295 TetR family transcriptional regulator (Pseudomonas putida KT2440)
MSTIRERNKELILRAASEEFADKGFAATKTSDIAAKAGLPKPNVYYYFKSKDNLYREVLE
SIIAPIMQASTPFNADGDPKEVLSAYIRSKIRISRDLPHASKVFASEIMHGAPHLSPNQV
EQLNEQARHNIECIQRWIDRGQIAHVDAHHLMFSIWAATQTYADFDWQISAVTGKAKLAD
SDYDAAAETIIRMVLKGCEPEAA