Protein Info for PP_4217 in Pseudomonas putida KT2440

Annotation: outer membrane ferripyoverdine receptor FpvA, TonB-dependent

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 812 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF07660: STN" amino acids 63 to 110 (48 residues), 49.7 bits, see alignment 3.7e-17 PF07715: Plug" amino acids 156 to 253 (98 residues), 65 bits, see alignment E=1.2e-21 TIGR01783: TonB-dependent siderophore receptor" amino acids 158 to 812 (655 residues), 370.7 bits, see alignment E=8.6e-115 PF00593: TonB_dep_Rec_b-barrel" amino acids 328 to 777 (450 residues), 188.6 bits, see alignment E=6e-59

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to ppu:PP_4217)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88F81 at UniProt or InterPro

Protein Sequence (812 amino acids)

>PP_4217 outer membrane ferripyoverdine receptor FpvA, TonB-dependent (Pseudomonas putida KT2440)
MPTQRLRPHALALVIRRSLRLAAPMAVGLAGLPAIAQAQQVQFNVPAQPLASALLAFGSQ
SNLQVLYSPQDVEGKRSSALTGAMEPAAALSRLLQGTGVSYQIQGNQVTIHTREGGAAVE
LGATNIDGKGLGQTTENTGSYTTGSMQTATKLPLTLRETPQAVTVITRQRMDDQSMRSLD
DVVQATPGLRMSAARPANSEYFSRGFPINNLMFDGLPTTYNADWVAAADMAPYDRVEIVR
GATGMMQGAGNPSAAINMVRKRPTKDFQGSVTGSAGSWDNYRGELDLSGPLNDNGSVRGR
FVGAYNDKDSYQDYAGRERGLFYGITEFDLTDDTTLTVGASNQNDNNNINWGGLPVNRDG
SHVGYSRSRNMGYDWSYQDIDNTTVFAEVDHRFDNDWRLHLAASKNWSDFAMQGAVFERT
GSATNEGFRQRVFNQRRDYDQSTYDVYANGPFQLFDRQHELVVGASKREVKTSAHGGTVF
IPVDSLFSVNPSGIDKPNVDDIYNLSEHVEQEGAYVTTRLNIADPLKVILGARLDWYDNK
SVYSEINDGYYTNSDYKVTRNVTRYAGVIYDLDDHHSVYASYTDIFMPQSELARDRSIIR
PIEGKNYEIGIKGEYFDGALNASAAIFQIDQENRAAEASNQEGCVDITCYEASGKVRTHG
IDLELMGALTPNWQVGAGYTYSQTKYRKDADKNKEGTKFDTDLPEHLFKLSTTYTLPGEL
NQWRVGGNVYGQSSIFNKGSNSFGNYHIDQGAYAVVGLMVGYKVNKNLDTRLNLNNVFDK
KYYQGIASNNSWSPYDVYGDPRNFTITAKYSF