Protein Info for PP_4206 in Pseudomonas putida KT2440

Annotation: Major facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 118 to 139 (22 residues), see Phobius details amino acids 157 to 181 (25 residues), see Phobius details amino acids 193 to 212 (20 residues), see Phobius details amino acids 246 to 271 (26 residues), see Phobius details amino acids 283 to 305 (23 residues), see Phobius details amino acids 314 to 334 (21 residues), see Phobius details amino acids 340 to 363 (24 residues), see Phobius details amino acids 375 to 394 (20 residues), see Phobius details amino acids 400 to 421 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 22 to 230 (209 residues), 73.8 bits, see alignment E=1.3e-24 PF07690: MFS_1" amino acids 38 to 386 (349 residues), 114.6 bits, see alignment E=4.9e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_4206)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88F92 at UniProt or InterPro

Protein Sequence (441 amino acids)

>PP_4206 Major facilitator family transporter (Pseudomonas putida KT2440)
MTAIDTARPPRFSRGDHRTLGLAALGGALEIYDFIIFVFFALTLSQLFFPPEMPEWLRLL
QSFGIFVTGYLARPLGGILMAHFADHLGRKRVFSLSILMMALPCLLIGVMPTYADIGYAA
PLILLALRILQGAAVGGEVPSAWTFVAEHAPNGRRGYALGFLQAGLTFGYLLGALTATLL
AQLFTPQEILDYAWRYPFLLGGVFGVIGVWLRRWLSETPVFLALRARQEQPVTFPLRQVL
GEHRRALIPAALLTCVLTSAVVVLVVITPTVMQQRFGMSAGHTFALSSVGIVFLNIGCVL
AGLLVDRVGAWRALMLYSLLLPLGIGALYASLVGQWGMTWLAYALAGLSCGVVGVVPSVM
VGLFPAQIRVSGISFTYNVAYALWASTTPLALIALMPWSPWVCVGFCLIMGAVGLLTALY
FGRREPLVFAAEPIPVMCGDK