Protein Info for PP_4162 in Pseudomonas putida KT2440

Annotation: conserved membrane protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 30 to 48 (19 residues), see Phobius details amino acids 58 to 80 (23 residues), see Phobius details amino acids 152 to 172 (21 residues), see Phobius details amino acids 221 to 249 (29 residues), see Phobius details amino acids 269 to 290 (22 residues), see Phobius details amino acids 302 to 329 (28 residues), see Phobius details PF01594: AI-2E_transport" amino acids 11 to 338 (328 residues), 152.7 bits, see alignment E=7.3e-49

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_4162)

Predicted SEED Role

"Putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88FD6 at UniProt or InterPro

Protein Sequence (350 amino acids)

>PP_4162 conserved membrane protein of unknown function (Pseudomonas putida KT2440)
MVNNDRLLVQILLVALLGAGLWVMAPFISALLWGAILAFASWPLMRFLTRLLGGRETLAA
GLLTMAWILIVALPLVWLGFNLADHIRDATAFVRDVQVDGLPDAPAWLGGIPFVGERLVN
GWQSLDQKGAALLTSIKPYFGQVGNWLLARSAQIGSGVLELTLSLVFVFFFYRDGPRLAA
FVLRLLHRLVGERAEYYLDLVAATVQRVVNGVIGTAAAQALLALIGFLIAGVPGAIVLGL
VTFMLSLIPMGPPLAWIPATAWLVWKGEYGMAVFLGVWGTFVISGVDNVLKPYLISRGGN
LPLVIVLLGVFGGLLAFGFIGLFIGPTLLAVGYSLLLDWSRNAAQQPPQQ