Protein Info for PP_4113 in Pseudomonas putida KT2440

Annotation: conserved exported protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 569 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00082: Peptidase_S8" amino acids 286 to 512 (227 residues), 78.3 bits, see alignment E=3.4e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_4113)

Predicted SEED Role

"Subtilisin-like serine proteases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88FI3 at UniProt or InterPro

Protein Sequence (569 amino acids)

>PP_4113 conserved exported protein of unknown function (Pseudomonas putida KT2440)
MKGVLILLLWLCSLGAQAAADTLRIKQLQRCGDLFSDSQQRWCLCAEGLRANLPTVWLGG
TRLSEADIERQGDRLTLKLARQAQRSAPLWLADGGRTSNPVWLTRQRSHVIAAGPDEVAK
NMDGLTTYVDLVSLLIEEKYDGLGEARRIAGKYGAQVVGAIPPLNVYQLRLPVEDLVQRD
AMVLRMGSEVSVDAVIVEESAPERGEEGNGRGTRAIDQADEWAANRFMDALYFYRRRIAA
SGLPVKPVRVGVIEREVDFDAPGFSHYRGGCEQGQTCLYARDGNRPASHGSHVAGILAAQ
GEGFLPGLGKHSPGFEVMVERNSDAGITANIAASVNLVEDGVRVLNWSWGIHRVGARDVN
GDEVDSLVRSGLAMSGYEELLEEFFLWLRKEHPDVVVVNSAGNGASWSGTDEYRLPSSFI
TEQLLVVGGHQRSGKATAVEAHDHVRKRHSSNIDMRVDVSAAACIRPVSAEAAHCGTSYA
TPLVTATVATMLSINPALTPEQVRMLLRRSALTLGAEQDFEAMDAEDLTAPILPSERGGR
LNDPDLGRSARLDMQRALDLAVQSLERVR