Protein Info for PP_3835 in Pseudomonas putida KT2440

Annotation: Sensory box histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 PF00989: PAS" amino acids 16 to 128 (113 residues), 51.8 bits, see alignment E=2.3e-17 TIGR00229: PAS domain S-box protein" amino acids 16 to 138 (123 residues), 72.9 bits, see alignment E=1.3e-24 PF13426: PAS_9" amino acids 28 to 130 (103 residues), 59.5 bits, see alignment E=1e-19 PF08448: PAS_4" amino acids 28 to 133 (106 residues), 47.7 bits, see alignment E=4.9e-16 PF08447: PAS_3" amino acids 39 to 124 (86 residues), 27.5 bits, see alignment E=9e-10 PF00512: HisKA" amino acids 154 to 215 (62 residues), 32.2 bits, see alignment E=2.7e-11 PF02518: HATPase_c" amino acids 260 to 376 (117 residues), 80.3 bits, see alignment E=4.4e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3835)

Predicted SEED Role

"sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88G90 at UniProt or InterPro

Protein Sequence (386 amino acids)

>PP_3835 Sensory box histidine kinase (Pseudomonas putida KT2440)
MVSADCLDASVMPAHRYEQLVQSVVDYAIYMLDPSGHVVSWNAGAQRIKGYRRDEVIGKH
FSLFFTPQDCADGRPERLLCQALEQGVAQDEGWRVRKDGTQFWALAALDVIRDESGQIIG
LAKVTRDITDRRETAQQLDAVRAQLFQAQKLEALGQLTGGLAHDFNNMLTIIISSARLAL
ATQDPARTQRMLQHILDASQRGTELTQQLLSFARHRKFDVASVAPAELVNATRGLLEHAL
PSSIDLKVLLQPDLPLIEVDAGQLQMVLLNLLFNARDAIDGHGRISLTVDVVELFGEVEG
LKGSFVRFEVEDSGEGIPTEILPRIFEPFFTTKPFGKGTGLGLSQVYGFARQSGGAICVD
SEPGRGTCMRLYLPMYQNQTDSPLDR