Protein Info for PP_3649 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 PF00392: GntR" amino acids 21 to 81 (61 residues), 60.6 bits, see alignment E=1.4e-20 PF07729: FCD" amino acids 91 to 214 (124 residues), 82.8 bits, see alignment E=4.3e-27

Best Hits

KEGG orthology group: None (inferred from 99% identity to ppf:Pput_2081)

Predicted SEED Role

"Predicted regulator PutR for proline utilization, GntR family" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88GR9 at UniProt or InterPro

Protein Sequence (250 amino acids)

>PP_3649 Transcriptional regulator, GntR family (Pseudomonas putida KT2440)
MKRQPLDDSFKVNRNPVTLREIVLDKLRTAIMNFHLLPGDRLVERDLCDRLGVSRTSVRE
ALRHLESEGLVEFADAKGPRVAIITLEDARDIYELRCVLEGLIVQLFTLNAKAKDIRALE
RALEVNREALEEGELQQVLDSVQGFYDVLLEGSGNQVAAQQLRQLQARISYLRATSVSQE
NRRGASNREMEKIVEAIKGGDPLVAHQASVDHVRAAAKVALDYLRQKQDDNAKVRDIVEP
LALKEPRIGR