Protein Info for PP_3641 in Pseudomonas putida KT2440

Annotation: Cytosine/purine/uracil/thiamine/allantoin permease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 32 to 52 (21 residues), see Phobius details amino acids 59 to 82 (24 residues), see Phobius details amino acids 102 to 125 (24 residues), see Phobius details amino acids 137 to 161 (25 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 197 to 217 (21 residues), see Phobius details amino acids 239 to 264 (26 residues), see Phobius details amino acids 276 to 294 (19 residues), see Phobius details amino acids 300 to 318 (19 residues), see Phobius details amino acids 326 to 345 (20 residues), see Phobius details amino acids 351 to 375 (25 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details amino acids 434 to 451 (18 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 18 to 439 (422 residues), 155.8 bits, see alignment E=8.7e-50

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 100% identity to ppu:PP_3641)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88GS7 at UniProt or InterPro

Protein Sequence (467 amino acids)

>PP_3641 Cytosine/purine/uracil/thiamine/allantoin permease family protein (Pseudomonas putida KT2440)
MSQPSSQHQFVENHTVDYVPPAERHGKARDLFTLWFSTNIAPLPIVTGAMVVQVFHLNLL
WGLIAIVLGHLVGGVVIALASAQGPQLGIPQMVQSRGQFGRYGALLIVFFTALIYVGFFI
SNIVLAGKTIHGIAPSVPMPGAIVIGALSATAIGVIGYRFIHILNRIGTWVMGSALLAGF
IMMFIQDLPADFFSRGAFNLSGFIATVSLGTIWQISFSPYTSDYSRYLPREVGIAKPFWA
TYLGATLGTILCFSFGAVAVLCVPQGTDAMDAVKQATGWLGPILMVLFLLNIISHNALNL
YGAVLSIVTAIQTFVAEWTPSVKVRVILASVILVGCGMVALNASADFIGQFIGLILALLL
VLVPWASINLIDFYLIKKGQYDIASIFSADGGIYGRFNHHAIIAYACGILVQLPFANTSL
YVGPYSNIVEGADLSWLFGLLVTVPLYYCLATRGKAVNSARVISVND