Protein Info for PP_3593 in Pseudomonas putida KT2440
Updated annotation (from data): L-lysine and D-lysine ABC transporter, substrate-binding component
Rationale: Specifically important for utilization of L-lysine and D-lysine.
Original annotation: Amino acid ABC transporter, periplasmic binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 98% identity to ppg:PputGB1_2323)Predicted SEED Role
"Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q88GX4 at UniProt or InterPro
Protein Sequence (250 amino acids)
>PP_3593 L-lysine and D-lysine ABC transporter, substrate-binding component (Pseudomonas putida KT2440) MNKSMALLGACALLLAGAASAETLRFATEGAYPPFNYVDADNKLHGFDVDITHALCEQMK VECTLVAQDWEGIIPALMARKYDAIVASMIDTEERRKKIAFTDHYYRTPLTVAVAKDSKI DSAQTDFVGYTVGAQSSSTQAIYAEDVYGKAGADVKLYPTMDEANADLAAGRLDGVIADK FPLHEWMNKNGGDCCKILGDVADTKADAAIAVRKDDEALRQRLNTALQQIVANGTYQKIA SKYFAFDIYN