Protein Info for PP_3589 in Pseudomonas putida KT2440

Annotation: serine:H+ symport permease, threonine-insensitive

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 transmembrane" amino acids 30 to 48 (19 residues), see Phobius details amino acids 54 to 73 (20 residues), see Phobius details amino acids 98 to 123 (26 residues), see Phobius details amino acids 143 to 161 (19 residues), see Phobius details amino acids 170 to 189 (20 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 255 to 277 (23 residues), see Phobius details amino acids 301 to 323 (23 residues), see Phobius details amino acids 344 to 362 (19 residues), see Phobius details amino acids 367 to 368 (2 residues), see Phobius details amino acids 370 to 391 (22 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details TIGR00814: serine transporter" amino acids 23 to 415 (393 residues), 532.7 bits, see alignment E=3.1e-164 PF03222: Trp_Tyr_perm" amino acids 35 to 392 (358 residues), 43.6 bits, see alignment E=1.1e-15

Best Hits

KEGG orthology group: K03837, serine transporter (inferred from 100% identity to ppf:Pput_2183)

Predicted SEED Role

"Serine transporter" in subsystem Glycine and Serine Utilization or Pyruvate Alanine Serine Interconversions or Threonine anaerobic catabolism gene cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88GX8 at UniProt or InterPro

Protein Sequence (426 amino acids)

>PP_3589 serine:H+ symport permease, threonine-insensitive (Pseudomonas putida KT2440)
MNEQAPSVEQRFAESTPAALGTWARHDTTWMLGLFGTAIGAGTLFLPINAGLGGFWPLLI
LAVLAFPMTYFAHRGLTRFVLSGRDGSDITEVVKEHFGITAGASITVLYFFAIFPILLIY
SVALTNTVSSFMEHQLHMQPPPRAILSFVLILGLLAIVRCGEQATVKVMSLLVYPFIVAL
ALLGLYLVPHWTGGILDSATEVPPASAFLHTLWLAIPVMVFSFNHSPIISAFAVDQKRRY
GAHADERSGQILRRAHLLMVVMVLFFVFSCVLTLSSAQLAEAKAQNLSILSYLANHFSNP
TIAFAAPLIAFVAIAKSFLGHYIGASEGLKGIIAKTGARPGAKALDRVVAALMLVVCWIV
ATLNPSILGMIESLGGPILAVLLFLMPMYAIRRVPSMRKYSGAASNVFVVVVGLVALTSV
VYGLVS