Protein Info for PP_3543 in Pseudomonas putida KT2440

Annotation: Iron-sulfur cluster-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 38 to 58 (21 residues), see Phobius details amino acids 85 to 106 (22 residues), see Phobius details amino acids 159 to 177 (19 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details amino acids 334 to 354 (21 residues), see Phobius details TIGR02745: cytochrome c oxidase accessory protein CcoG" amino acids 35 to 464 (430 residues), 570.9 bits, see alignment E=9.6e-176 PF12801: Fer4_5" amino acids 91 to 117 (27 residues), 22.8 bits, see alignment (E = 2.1e-08) amino acids 196 to 232 (37 residues), 8.3 bits, see alignment 0.00072 PF13746: Fer4_18" amino acids 213 to 319 (107 residues), 144.4 bits, see alignment E=5e-46 PF13534: Fer4_17" amino acids 217 to 281 (65 residues), 22.3 bits, see alignment E=4.6e-08 PF11614: FixG_C" amino acids 348 to 464 (117 residues), 95.8 bits, see alignment E=6.2e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3543)

Predicted SEED Role

"Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation" in subsystem Biogenesis of cbb3-type cytochrome c oxidases or Terminal cytochrome C oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88H22 at UniProt or InterPro

Protein Sequence (467 amino acids)

>PP_3543 Iron-sulfur cluster-binding protein (Pseudomonas putida KT2440)
MNDRIPFTEIATAPASIQARRTDSGIHTRSFTGLYRNLRIGFAGALFVLFFGTAWLNWNG
RQAVLWDLGNSKFHIFGATFWPQDFILLSALLIICAFGLFAITVYAGRVWCGYSCPQSTW
TWLFMWCEKVTEGDRNQRIKLAAAPWSLNKLARRTLKHSLWLAIGVLTGLTFVGYFTPIR
PLAAELLTLQLGGVALFWVLFFTAATYINAGLLREAVCLHMCPYARFQSVMFDKDTLAVA
YDPRRGEARGPRKKGSDVGAQGLGDCIDCTLCVQVCPTGIDIRDGLQMACIGCAACIDAC
DGVMDKMGYARGLIGYKSEHSLQGGTTHWLRPRLLGYAAALLVMIGALVVALQMRPMVSL
DVIKDRGLFRENAQGQIENIYLLKVINKTERTQHYQLRLLDADGFTLQGSSALVIPAGEM
SELPVSVAMLAERPSSSSQTLSFEISERDDPAIRSVAHSRFVAPMNR