Protein Info for PP_3368 in Pseudomonas putida KT2440

Annotation: Major facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 58 to 77 (20 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 109 to 135 (27 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 172 to 192 (21 residues), see Phobius details amino acids 213 to 237 (25 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 280 to 298 (19 residues), see Phobius details amino acids 303 to 323 (21 residues), see Phobius details amino acids 343 to 363 (21 residues), see Phobius details amino acids 369 to 387 (19 residues), see Phobius details PF07690: MFS_1" amino acids 22 to 333 (312 residues), 142.8 bits, see alignment E=1.9e-45 PF06779: MFS_4" amino acids 27 to 383 (357 residues), 32.4 bits, see alignment E=9.8e-12 PF00083: Sugar_tr" amino acids 50 to 189 (140 residues), 33.5 bits, see alignment E=3.6e-12

Best Hits

KEGG orthology group: K08156, MFS transporter, DHA1 family, arabinose polymer transporter (inferred from 100% identity to ppu:PP_3368)

Predicted SEED Role

"MFS transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88HI9 at UniProt or InterPro

Protein Sequence (394 amino acids)

>PP_3368 Major facilitator family transporter (Pseudomonas putida KT2440)
MSVQEHPPLPSKNTVAKMEAAMALGSFAIGTGEFAIMGLMPDIASNLQLSEPQVGHAISA
YALGVMVGAPTLAILGAKLLRKHMLLLLMLLYAVGNLATAFAPSFGGLVAFRFISGLPHG
AYFGIAAVVASSMVAKDQRAGAVARVMMGLTLAMLLGNPVATFLGQYFGWRSAFVLVGAI
ALCTIALVWRFVPQRHDETRSDPRKELQAFALPQVWMALAIASIGFAGMFCVFSYLAPTM
LQVTQVSPQWIPFGLAAFGVGGIVGNIAGGKLFDRLQFRAVGLVLMWSVAVLLFFTFAAQ
ALWSLLLGIGLVGTMIALAAPLQIRLMDIAHEAPSLAAASNHAAFNLANALGPWLGGMAI
TAGMGWTSTGYIGAATALVGLGIYLVARRMKGGH