Protein Info for PP_3364 in Pseudomonas putida KT2440

Annotation: Response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 847 PF08446: PAS_2" amino acids 12 to 118 (107 residues), 103.1 bits, see alignment E=4.3e-33 PF01590: GAF" amino acids 143 to 299 (157 residues), 54.5 bits, see alignment E=5.5e-18 PF00360: PHY" amino acids 321 to 500 (180 residues), 186.3 bits, see alignment E=1e-58 PF07536: HWE_HK" amino acids 520 to 600 (81 residues), 74.9 bits, see alignment E=2.1e-24 PF07568: HisKA_2" amino acids 520 to 571 (52 residues), 24.5 bits, see alignment 6.9e-09 PF00072: Response_reg" amino acids 734 to 821 (88 residues), 36.1 bits, see alignment E=1.9e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3364)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-)" in subsystem Oxidative stress or Oxygen and light sensor PpaA-PpsR (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88HJ2 at UniProt or InterPro

Protein Sequence (847 amino acids)

>PP_3364 Response regulator (Pseudomonas putida KT2440)
MTYNPQVNLTNCDREPIQIPGSIQPHGCLLACDASATVVLRHSVNAPQMLGVANDINGQK
LHAVLGDEVTHTLRNALARTRDASRPALSFGVTLPNGAAVDIAAHLYKGTAILEFEPAGA
SIAEPIELARTLIAQLREIDQTHKLFRDAARFVRAVLGYDRVMIYQLGADGAGKVVAESK
RSDLESFMGQYFPASDIPQQARALYLRNPIRVISDAQFNTVAINPVLDPSGEPLDLSYAH
LRSVSPIHCEYLCNMGVGASMSISVIVNGELWGMIACHHYAPRTLAMGQRVAAEMFGEFF
SLHIETLRSRQKLEAAVRIHKALDSLLRDANQAADIDGFFHARLPRLMSLIPCDGIGMSL
LGRWSCAGLAPPQTAVPDLLRLADMVSEGRIWASNRLSTVLPSAQAYFNDVSGVLIIPMS
QHPRDYLIFFRKEVVETLDWAGDPNKTYDSGALGDRLTPRKSFAIWKETVHQQSLPWTEQ
DRQFGDAIRTAIVEVVLHNSELLASERAKADVRQRMLNEELNHRVKNILSLIGALVAHPT
PESQTLQDYVATLKGRIQALSLAHDQVVRGDGGGRLAKLLEAELSPYRTAADVIELQGPN
VILDARAYSVMALVLHELATNAAKYGALSRAGGKLSVSWAIDASNACAISWREMGGPTVR
PPSRSGFGTVLIDRSIPFDLGGTSAVEYHPEGLQGFFRIPAKHLSVAEAAETALPATPLA
RANGAFAARSGLCVLILEDQLVIAVGLEQILNDAQIKDVITASSEDQAMQLLGSHKPDAA
ILDVNLGTGTSISVADELVRRQVPFLFATGYGDGISIPEHLQHVPVARKPYDANAILASL
QSLLELG