Protein Info for PP_3349 in Pseudomonas putida KT2440

Annotation: 3-hydroxyphenylpropionate / 3-hydroxycinnamate:H+ symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details transmembrane" amino acids 52 to 72 (21 residues), see Phobius details amino acids 79 to 99 (21 residues), see Phobius details amino acids 105 to 126 (22 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 167 to 187 (21 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details amino acids 280 to 301 (22 residues), see Phobius details amino acids 307 to 330 (24 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 364 to 365 (2 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details PF07690: MFS_1" amino acids 19 to 278 (260 residues), 133.1 bits, see alignment E=1.2e-42 amino acids 248 to 407 (160 residues), 41.7 bits, see alignment E=7.2e-15 PF00083: Sugar_tr" amino acids 49 to 220 (172 residues), 74.9 bits, see alignment E=6.3e-25

Best Hits

KEGG orthology group: K05819, MFS transporter, AAHS family, 3-hydroxyphenylpropionic acid transporter (inferred from 100% identity to ppu:PP_3349)

Predicted SEED Role

"Putative hydroxycinnamate transporter" in subsystem Phenylpropanoid compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88HK7 at UniProt or InterPro

Protein Sequence (413 amino acids)

>PP_3349 3-hydroxyphenylpropionate / 3-hydroxycinnamate:H+ symporter (Pseudomonas putida KT2440)
MHHSCASSGKAVLTIGLCFLVALLEGLDLQATGIAAPHMAKAFNLTPAMLGWVFSAGLLG
LLPGALIGGWLADRFGRKAILIVAVLLFGGFSLGTAHAQTYDSLLIARLMTGLGLGAALP
ILIALASEAAPERLRSTAVSLTYCGVPLGGAVASLIGMAGVGDGWRTVFYVGGIAPIVIA
FVLMIWLKESQAFRAQGVAKAGSEGVLAQLFGPQQASRTLLLWVACFFTLTVLYMLLNWL
PSLLIGQGFSRPQAGAVQILFNLGGAAGSFLTGRMMDRGFAGRAVLIAYAGMLASLAGLG
LSSSFGLMLLAGFTAGYCAIGGQLVLYALAPTLYSTQVRATGLGASVAVGRLGSMAGPLA
AGQILAAGAGAGGLLMAAAPGLVLAALAARALLKHRTRTQRPEPGEAAAQDPA