Protein Info for PP_3323 in Pseudomonas putida KT2440

Annotation: CobW/P47K family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 PF02492: cobW" amino acids 15 to 160 (146 residues), 159 bits, see alignment E=4.8e-51

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3323)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88HN0 at UniProt or InterPro

Protein Sequence (203 amino acids)

>PP_3323 CobW/P47K family protein (Pseudomonas putida KT2440)
MSTPAPHTNEAARLPVTVLSGFLGAGKTTLLNHILNNREGRRVAVIVNDMSDVNIDAALI
RKGGAELSRTDEKLVEMSNGCICCTLREDLLLEVDRLAKEGRFDQLVIESTGISEPLPVA
ETFTFEGEDGRSLSEVARLDTMVTVVDAFNFLRDYSSRDSLQARGESLGEEDVRTVVDLL
TDEEMAQGPEGWIKLTNPFPGWN