Protein Info for PP_3220 in Pseudomonas putida KT2440

Annotation: ABC transporter, ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 PF00005: ABC_tran" amino acids 26 to 185 (160 residues), 109 bits, see alignment E=1.7e-34 amino acids 300 to 451 (152 residues), 118.6 bits, see alignment E=1.9e-37 PF08352: oligo_HPY" amino acids 236 to 288 (53 residues), 24.2 bits, see alignment 2e-08 amino acids 503 to 529 (27 residues), 17.9 bits, see alignment (E = 1.7e-06)

Best Hits

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein K02032, peptide/nickel transport system ATP-binding protein (inferred from 100% identity to ppu:PP_3220)

Predicted SEED Role

"Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88HY3 at UniProt or InterPro

Protein Sequence (539 amino acids)

>PP_3220 ABC transporter, ATP-binding protein (Pseudomonas putida KT2440)
MSQSPLIEVRDLSVSYSFAGQRSQALRQLSFSLVQGETLAVVGESGSGKSTLANALLGLL
PGNARIDQGQLWVDGVDMAQASERARRQLRGRTIGLVPQDPMVSLNPTQRIGQQIAEALQ
LARGRRYPGQEAKVLALLDQVGLDEPALRARQYPHELSGGMRQRVLIAIALAGEPRLIIA
DEPTSALDVTVQRRILDHLQLLVAERGISLLIITHDLGMACDRADRLLVMKQGEQVEHGS
PRQILWGARQPYTRALLDAAPAFVPRRRPAAPRGQTPLLRLSHVGKRFELPGKNEHYTAL
HDLSLELHAGQTLAIVGESGSGKSTALRIALGLEKPSQGQVVFAGEDVTGYTWSQFRPLR
RRIQLVQQNPFAALDPRFTVFDSVVEPLVSFGLLRGEALERKARELITRVQLPVQFLDRL
PRELSGGQRQRVAIARALALEPEVLLLDEPVSALDVSVQAQILALLDELQRELGMAYVLV
SHDLAVVASMADQVLVLRRGQVVEQGPALQVLSKSASAYTRALIDAIPGHSRSMLPVAI