Protein Info for PP_3176 in Pseudomonas putida KT2440

Annotation: Major facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 22 to 39 (18 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details amino acids 150 to 173 (24 residues), see Phobius details amino acids 185 to 208 (24 residues), see Phobius details amino acids 253 to 275 (23 residues), see Phobius details amino acids 287 to 306 (20 residues), see Phobius details amino acids 318 to 337 (20 residues), see Phobius details amino acids 343 to 363 (21 residues), see Phobius details amino acids 370 to 396 (27 residues), see Phobius details amino acids 409 to 428 (20 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 394 (365 residues), 160.4 bits, see alignment E=2.9e-51

Best Hits

Swiss-Prot: 47% identical to TUB4_AGRVI: Putative tartrate transporter (ttuB) from Agrobacterium vitis

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3176)

Predicted SEED Role

"D-glycerate transporter (predicted)" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88I26 at UniProt or InterPro

Protein Sequence (440 amino acids)

>PP_3176 Major facilitator family transporter (Pseudomonas putida KT2440)
MAHSPAPDQGTDTTRNALYRRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALKFSET
VYGLGAGIFFIGYVLCGLPSNLALNRFGPRRWIALMMIAWGSLSTCLLFVTTPTEFYTLR
LLTGAAEAGFFPGVVLYLSRWFPAARRGRIMALFMSAIPVSGLLGGPFSGWILEHFAAGQ
HGLAGWQWMFLIQGLPTVALGVLAVFLLSDGYQKAAWLSPAERQLIAADLQADAASKPST
TSDSVLAVLTNPLIWTFGFVYFCIQSGVYAINFWLPSIIKGFDNPLLIGWLSAIPYLLAG
VFMILCGRSADLRNERRWHLVVPMLMGAVGLLIAVNFAGNPTIAILGLSIATMGALTGLP
MFWPMPTALLSAGAAVAGLAIINSVGQMAGFLSPYLVGFIKDQTGSTDAALYSLAALIVL
GSLVALRVTRAGSLSTARAS