Protein Info for PP_2880 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, TetR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 transmembrane" amino acids 29 to 41 (13 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details PF00440: TetR_N" amino acids 21 to 61 (41 residues), 38.1 bits, see alignment 5.3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2880)

Predicted SEED Role

"Transcriptional regulator, TetR family, in cluster with 2-hydroxychromene-2-carboxylate isomerase family protein, glutathione-dependent"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88IW9 at UniProt or InterPro

Protein Sequence (187 amino acids)

>PP_2880 Transcriptional regulator, TetR family (Pseudomonas putida KT2440)
MRYSNEHKQQTRERLLASSGALAKRGGFASTGVAGLMKAIGLTGGAFYNHFPSKDDLFTE
VVRQELSNSPLARLASKGANRERLGRCLQQYLSLVHLRNAEGGCPLPPLGVEIARADTPV
REVAEHWLVELHRAWSTTLEDEQLAWVLISQCVGALLVGRMLASESVQAQVLGASRQFVE
QALHEAD