Protein Info for PP_2672 in Pseudomonas putida KT2440

Annotation: Transcriptional activator protein ExaE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 PF00072: Response_reg" amino acids 3 to 115 (113 residues), 98.5 bits, see alignment E=2.7e-32 PF00196: GerE" amino acids 148 to 201 (54 residues), 53.7 bits, see alignment E=1.3e-18

Best Hits

Swiss-Prot: 72% identical to EXAE_PSEPU: Transcriptional activator protein ExaE (exaE) from Pseudomonas putida

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_3091)

MetaCyc: 32% identical to DNA-binding transcriptional dual regulator NarL (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88JH7 at UniProt or InterPro

Protein Sequence (212 amino acids)

>PP_2672 Transcriptional activator protein ExaE (Pseudomonas putida KT2440)
MNIVLVDDHAVVRQGYASLLRAVLPLVQVREAASGEEALVRVQEQVPNLVIMDFGLPGIS
GLETTRRLRQRLPQLRVLFFSMHDELPLVRQALDAGASGYLTKNSAPEVLIEAVQRVLAG
HAYIEQPLATQLACLSQQSTSDPRLQRMTQRELEIFTMLAKGTPARVIAEQLCISAKTVS
NHLTLLKSKLQVSSHAELVHLGIDLGVVRVAG