Protein Info for PP_2604 in Pseudomonas putida KT2440

Annotation: major facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 32 to 52 (21 residues), see Phobius details amino acids 71 to 90 (20 residues), see Phobius details amino acids 101 to 127 (27 residues), see Phobius details amino acids 131 to 131 (1 residues), see Phobius details amino acids 184 to 207 (24 residues), see Phobius details amino acids 248 to 268 (21 residues), see Phobius details amino acids 288 to 311 (24 residues), see Phobius details amino acids 321 to 340 (20 residues), see Phobius details amino acids 346 to 370 (25 residues), see Phobius details amino acids 379 to 401 (23 residues), see Phobius details amino acids 412 to 432 (21 residues), see Phobius details PF07690: MFS_1" amino acids 39 to 396 (358 residues), 177.3 bits, see alignment E=2.1e-56

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 100% identity to ppf:Pput_3121)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88JP5 at UniProt or InterPro

Protein Sequence (441 amino acids)

>PP_2604 major facilitator family transporter (Pseudomonas putida KT2440)
MNHSKIPPAAPRMSQGSIGDKLRGAFGVGKTRWGMLALVFFATTLNYIDRAALGIMQPVL
AKEMSWTAMDYANINFWFQVGYAIGFLLQGRLIDKVGVKRAFFFAVLLWSLATGAHGLAT
SAAGFMVCRFILGLTEAANYPACVKTVRLWFPAGERAIATGLFNAGTNVGAMVTPALLPL
ILAVWGWQAAFIAMGSLGLVWVVFWVLKYYNPEDHPRVRQSEVQYIQQDDEPEPTRVPFS
RILRLRGTWAFAVAYAITAPVFWFYLYWLPPFLNQQYSLGINVTQMGIPLIIIWLTADFG
SIGGGILSSWLIGRGVRATTARLVSMLIFACTMLSVIFAANASGLWVAVAAISIAVGAHQ
AWTANIWSLVMDYTPKHLVSTVFGFGSMCAAIGGMFMTQIVGSVLTATNNNYAVLFTMIP
AMYFLALVWMYFMAPRKVESA