Protein Info for PP_2542 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 PF00392: GntR" amino acids 13 to 75 (63 residues), 53.9 bits, see alignment E=1.2e-18 PF00155: Aminotran_1_2" amino acids 141 to 463 (323 residues), 139.6 bits, see alignment E=1.5e-44

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_3172)

Predicted SEED Role

"Transcriptional regulator GabR of GABA utilization (GntR family with aminotransferase-like domain)" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88JV5 at UniProt or InterPro

Protein Sequence (474 amino acids)

>PP_2542 Transcriptional regulator, GntR family (Pseudomonas putida KT2440)
MFELHPDSSTPLVNQIIDGLRELIDNQTLKPGAKVPSIRAFAASYSVSTFTVVEAYDRLV
AQGLLVSRGNAGFFVNRAAGELLEQHNTEADTSRPTFNSEWYLQQIFEIRQLPYKPGCGW
LPNDWMYEDGLRRGLRQVAGSPLELSGYGDPMGLMELRALTAQNLQQELSIVANPAQLML
THGASQALDLAARTLVRPGDVVLVDDPGYPNLMSILRTQGATLVGVPRTPAGYDLNQLEQ
LLSHHRPTAFFTQPHLHSPTCSRTPLPQLHRLLQLASQHGFRLVENNLYADMVAEPQPCL
ASLDHLQQVVYVGSYSKSISPNVRVGYMLANPELMQKLLHLKMRSGLTTSQVMERVVYAA
IIDGRWRKHLKRLRQRLAEAHQEVGRHLHRLGFELFTESDEGMYIWTRHPAIPDSAALLD
DALEKGIMLGPGQLFMVDAKATGWMRFNVAFSTDPAMWELLEKVLVKHVRRSGM