Protein Info for PP_2539 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00126: HTH_1" amino acids 14 to 73 (60 residues), 56.3 bits, see alignment E=2.5e-19 PF03466: LysR_substrate" amino acids 99 to 304 (206 residues), 118.4 bits, see alignment E=2.9e-38

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2539)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88JV8 at UniProt or InterPro

Protein Sequence (308 amino acids)

>PP_2539 Transcriptional regulator, LysR family (Pseudomonas putida KT2440)
MIPSLDAIFSRLRLRQLRLLIELDRCGSLHKAAEAMAISQPGATKALREVEEVLGVPLFQ
RMPSGLVANDVGRCVVRYARLIHSDLGHLREEVLGIVQGQGGRLAVGSIMGAMPTLVSAL
GRLRRKQPQLAVEIAENTSANLLAQLDEGRLDLAICRPGLGRNAAEYGFVELTQEPLAVV
AHPQHPLAGAAALKISDLSHYRWVVYPANMPMRQALERELSEAGVEVSRYPLETFSTFAT
FMLLEDDPTLVAVIPRAVAAFAEQRGLLVSLAVPLRALSEPFGIVHRVAAPLSPAARLLV
EELTAGEV