Protein Info for PP_2376 in Pseudomonas putida KT2440

Annotation: Esterified fatty acid cis/trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 766 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF06934: CTI" amino acids 84 to 765 (682 residues), 977.3 bits, see alignment E=2.6e-298

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2376)

Predicted SEED Role

"cis/trans isomerase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88KB4 at UniProt or InterPro

Protein Sequence (766 amino acids)

>PP_2376 Esterified fatty acid cis/trans isomerase (Pseudomonas putida KT2440)
MVHRILAGAFALLISGAVFGQAPQSSPAISYTRDIQPIFTEKCVACHACNDAACQLKLES
PEGAVRGASKVPVYQGERSKAVPTTRLFYDAHSEEQWRKKGFYSVLDNQGGQAALMARML
ELGHKTPLTPNAKLPEEIVLGLSRNNMCPLPHEFDAYAGAHPKEGMPLAVTGLTDKEYDT
MRRWLAAGAPVEYQPIQPSAAEARQIAEWEELLNRPGSTEALVGRWLYEHLFLAHIHFAG
GEQGHFFQWVRSRTPSGKPVDIIATRRPNDPPGTDFYYRLIPVQGVIVHKTHITYPMGPQ
KLKRVKQLFYAGDWHAAALPGYGPRHRANPFETFEAIPAVARYQFMLDNAEYFVRTFIRG
PVCRGQIATDVIRDNFWALFQEPAFDRYITDAKYRGEATPLLAMPGQIDDVGSVLSLWHA
YRDKRNDYEKLRREAYAEMPAPRWSTLWAGNDNALLSIFRHFDSASVTKGLVGDVPLTVW
LFDYPLFERTYYQLAVNFDVYGNVSHQLQTRLYFDLIRNGAEVNFLRLMPADQRKAILGD
WYQNSGKVKMWMDYEDIDTDTPSGIKLDPRNPKRDFGLKLLQRTGSLNAAPDPINRCQGA
FCSRPQMSEEFRNAEQSLSRLVSRPAAGLKVINQLPEATMLRIEGQDGQRQVYSLLRNRA
HSNVAFLLGEAYRYQPGLDTLTLYPGVLSSYPNFIFNIPTKDVPEFVEDMEYAKDDAAKF
ERIVMRWGVRRSHPAFWRYFHDLNSYIKETEPVEAGVLDMNRYENL