Protein Info for PP_2352 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF03969: AFG1_ATPase" amino acids 79 to 372 (294 residues), 301.6 bits, see alignment E=3.7e-94

Best Hits

KEGG orthology group: K06916, (no description) (inferred from 100% identity to ppu:PP_2352)

Predicted SEED Role

"ATPase component BioM of energizing module of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88KD8 at UniProt or InterPro

Protein Sequence (375 amino acids)

>PP_2352 conserved protein of unknown function (Pseudomonas putida KT2440)
MAALGQAAGCPAIAQGALLLSAWIPTPLRQLGQRLRGTANQQSELLGWFEDKAHSRGYQL
SDGQRRVIHCMAEQLTQLEQGQPRSLYLYGSVGRGKSWLLDGFFQAVPIAAKLRLHFHDF
FARLHQGMHRHRALDDALGATLDELVGGCRVLCFDEFHVHDIGDAMLLTRLFNALFARGV
YLLVTSNYAPEGLLPNPLYHERFLPVIRLINSSMHVLEVGGDTDFRSLPANREHQRFTQG
HYVWPGDAAQRQALNVPNEQPVILDVNKRPLRALAIDGRRVVLGFDDLCEKATAVIDYLV
LAREYDEWVIDGLDDLSACSLAAQQRFVNLVDVLYDQDRRVIVIGKRPLEESLGGPLADL
MRTRSRLGQLHQIAP