Protein Info for PP_1954 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF00144: Beta-lactamase" amino acids 16 to 369 (354 residues), 174.9 bits, see alignment E=1.3e-55

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_1954)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88LH8 at UniProt or InterPro

Protein Sequence (388 amino acids)

>PP_1954 conserved protein of unknown function (Pseudomonas putida KT2440)
MSIKAGFDDRALARVEAAIRADVESGIYDGAVIKVARHGQIALDATIGFSNRRAGAAMRE
DAVFKVLSLTKAFTTTLVLEAIDLGLLSLTTRVVDVIPEFWGRDLFRSGRKERVNVGHLL
THRAGLSPTPQPLPYDQLHNFSETIQAICALDVVGEPGKAFNYSPTVNHALLGEMVRRVH
GAASLAELMDQRLFSRLGMSSTSLGPTSQIRDRLVPLTSDFPEGGWLTNADIKAVADAIE
APNSQMPWVGAMTSAQDVFVFAEMLREQGTVRDERILSPAVVRKATTLQTGDAINDLYKL
LADARHWDLPAGNMGLGFALGGDGLTVSQFGTLTSPGTFGNFGAGSTLFWVDPESQITFV
CLTAKVMEESENILRFQRLSDLVASAAL